T6167923
T6167923 is a potent and selective small molecule inhibitor that targets the MyD88 TIR domain, blocking homodimerization and downstream NF-κB signaling. It demonstrates anti-inflammatory activity in vitro by suppressing key cytokines including IFN-γ, IL-1β, IL-6, and TNF-α. This inhibitor is a valuable research tool for studying Toll-like receptor and interleukin-1 receptor pathways in inflammatory and autoimmune disease models.
Product Specifications
CAS Number
2437475-16-4
Product Name Alternative
T 6167923, T6167923, T-6167923, MyD88
Field of Research
Immunology & Inflammation
Purity
99.23% (May vary between batches)
Solubility
DMSO:250 mg/mL (545.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.91 mM)
Smiles
C[C@H] (NC (=O) N1CCN (CC1) S (=O) (=O) c1cccc (Br) c1) c1cccs1
Molecular Formula
C17H20BrN3O3S2
Molecular Weight
458.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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