TAS4464 hydrochloride
TAS4464 hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 0.955 nM. It is a valuable research tool for investigating the neddylation pathway in oncology research, demonstrating activity in both cellular and in vivo models of cancer.
Product Specifications
CAS Number
1848959-11-4
Product Name Alternative
Inhibitor, NEDD8-activating Enzyme, NEDD8, NAE, inhibit, E1Enzyme, E1 Enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, TAS4464, TAS-4464, TAS4464 Hydrochloride, TAS4464 hydrochloride, TAS-4464 Hydrochloride, TAS-4464 hydrochloride, TAS 4464, TAS 4464 Hydrochloride
Field of Research
Metabolism Research, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
30% PEG300+70% Saline:5 mg/mL (9.21 mM) ; H2O:4 mg/mL (7.37 mM) ; DMSO:80 mg/mL (147.34 mM)
Smiles
Cl.CCOc1cccc (F) c1C#Cc1cn ([C@@H]2O[C@H] (CNS (N) (=O) =O) [C@@H] (O) [C@H]2O) c2ncnc (N) c12
Molecular Formula
C21H24ClFN6O6S
Molecular Weight
542.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-57853-25ul 25 µL
Rabbit Polyclonal Mineralocorticoid R/NR3C2 Antibody
Sign In for Pricing
View Details ![Rabbit Polyclonal MTH1 Antibody [DyLight 350]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
ELI-35541m 96 Tests
Mouse Ras-related protein Rab-40B, Rab40b ELISA KIT
Sign In for Pricing
View Details 
219146-01 20 µL
PLSCR1 (Phospholipid Scramblase 1, MMTRA1B) discontinued
Sign In for Pricing
View Details 219146-02 100 µL
PLSCR1 (Phospholipid Scramblase 1, MMTRA1B) discontinued
Sign In for Pricing
View Details