TAS4464 hydrochloride
TAS4464 hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 0.955 nM. It is a valuable research tool for investigating the neddylation pathway in oncology research, demonstrating activity in both cellular and in vivo models of cancer.
Product Specifications
CAS Number
1848959-11-4
Product Name Alternative
Inhibitor, NEDD8-activating Enzyme, NEDD8, NAE, inhibit, E1Enzyme, E1 Enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, TAS4464, TAS-4464, TAS4464 Hydrochloride, TAS4464 hydrochloride, TAS-4464 Hydrochloride, TAS-4464 hydrochloride, TAS 4464, TAS 4464 Hydrochloride
Field of Research
Metabolism Research, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
30% PEG300+70% Saline:5 mg/mL (9.21 mM) ; H2O:4 mg/mL (7.37 mM) ; DMSO:80 mg/mL (147.34 mM)
Smiles
Cl.CCOc1cccc (F) c1C#Cc1cn ([C@@H]2O[C@H] (CNS (N) (=O) =O) [C@@H] (O) [C@H]2O) c2ncnc (N) c12
Molecular Formula
C21H24ClFN6O6S
Molecular Weight
542.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HP201274 200 Reactions
DUSP27 (DUPD1) Human qPCR Primer Pair (NM_001003892)
Sign In for Pricing
View Details MBS1432703-01 0.02 mg (E-Coli)
Recombinant Streptomyces avermitilis Carboxylate-amine ligase SAV_999 (SAV_999)
Sign In for Pricing
View Details MBS1432703-02 0.02 mg (Yeast)
Recombinant Streptomyces avermitilis Carboxylate-amine ligase SAV_999 (SAV_999)
Sign In for Pricing
View Details MBS1432703-03 0.1 mg (E-Coli)
Recombinant Streptomyces avermitilis Carboxylate-amine ligase SAV_999 (SAV_999)
Sign In for Pricing
View Details MBS1432703-04 0.1 mg (Yeast)
Recombinant Streptomyces avermitilis Carboxylate-amine ligase SAV_999 (SAV_999)
Sign In for Pricing
View Details MBS1432703-05 0.02 mg (Baculovirus)
Recombinant Streptomyces avermitilis Carboxylate-amine ligase SAV_999 (SAV_999)
Sign In for Pricing
View Details