TAS4464 hydrochloride
TAS4464 hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 0.955 nM. It is a valuable research tool for investigating the neddylation pathway in oncology research, demonstrating activity in both cellular and in vivo models of cancer.
Product Specifications
CAS Number
1848959-11-4
Product Name Alternative
Inhibitor, NEDD8-activating Enzyme, NEDD8, NAE, inhibit, E1Enzyme, E1 Enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E3Enzyme, TAS4464, TAS-4464, TAS4464 Hydrochloride, TAS4464 hydrochloride, TAS-4464 Hydrochloride, TAS-4464 hydrochloride, TAS 4464, TAS 4464 Hydrochloride
Field of Research
Metabolism Research, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
30% PEG300+70% Saline:5 mg/mL (9.21 mM) ; H2O:4 mg/mL (7.37 mM) ; DMSO:80 mg/mL (147.34 mM)
Smiles
Cl.CCOc1cccc (F) c1C#Cc1cn ([C@@H]2O[C@H] (CNS (N) (=O) =O) [C@@H] (O) [C@H]2O) c2ncnc (N) c12
Molecular Formula
C21H24ClFN6O6S
Molecular Weight
542.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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