Pamufetinib
Pamufetinib (TAS-115) is a dual kinase inhibitor targeting VEGFR2 and c-Met with high potency, exhibiting IC50 values of 30 nM and 32 nM, respectively. It is utilized in preclinical cancer research, including studies on angiogenesis and tumor growth in both cellular and animal models.
Product Specifications
CAS Number
1190836-34-0
Product Name Alternative
TAS115, TAS-115, TAS 115, Vascular endothelial growth factor receptor, VEGFR, VEGFR2, c-Met/HGFR, cMet, c-Met, cMet/HGFR, 4- (2-Fluoro-4- (3- (2-phenylacetyl) thioureido) phenoxy) -7-methoxy-N-methylquinoline-6-carboxamide, Pamufetinib, inhibit, H2OL3Q4XRD, Inhibitor, HGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.15% (May vary between batches)
Solubility
DMSO:13 mg/mL (25.07 mM)
Smiles
O (C=1C2=C (C=C (OC) C (C (NC) =O) =C2) N=CC1) C3=C (F) C=C (NC (NC (CC4=CC=CC=C4) =O) =S) C=C3
Molecular Formula
C27H23FN4O4S
Molecular Weight
518.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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