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TK216

TK216 is a potent and selective small molecule inhibitor of the E26 transformation-specific (ETS) family of transcription factors. It demonstrates anticancer activity in preclinical studies, showing efficacy in both in vitro cellular assays and in vivo xenograft models of ETS-dependent cancers.

Product Specifications

CAS Number

1903783-48-1

Product Name Alternative

Leukemia, Friend, Ewing, EWS-FLI1, EST, ETS, Inhibitor, inhibit, E26, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, anticancer, transcription, virus, TK216, TK-216, TK 216, proliferation, RNASynthesis, RNA, RNA Synthesis, sarcoma

Field of Research

Cell Biology, Molecular Biology

Purity

97.22% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.29 mM) ; DMSO:249 mg/mL (661.83 mM)

Smiles

OC1 (CC (=O) c2ccc (cc2) C2CC2) C (=O) Nc2c1c (Cl) ccc2Cl

Molecular Formula

C19H15Cl2NO3

Molecular Weight

376.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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