TMPA
TMPA is a small molecule antagonist that disrupts the interaction between the nuclear receptor Nur77 (NR4A1) and the kinase LKB1 (STK11) . This compound is a valuable research tool for investigating Nur77-LKB1 signaling in metabolic regulation, cancer, and inflammation, with utility in both cellular and animal models.
Product Specifications
CAS Number
1258275-73-8
Product Name Alternative
AMPKα, AMPK, AMP-activated protein kinase, Inhibitor, hepatic LO2, Nur77, LKB1, inhibit, TMPA, T cells, type II diabetes
Field of Research
Epigenetics & Chromatin, Metabolism Research, Musculoskeletal & Connective Tissue Research, Signal Transduction
Purity
98.08% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.67 mM) ; DMSO:90 mg/mL (236.54 mM)
Smiles
CCCCCCCC (=O) c1cc (OC) c (OC) c (OC) c1CC (=O) OCC
Molecular Formula
C21H32O6
Molecular Weight
380.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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