TNO155
TNO155 is a potent and selective small molecule inhibitor of the SHP2 (PTPN11) phosphatase, exhibiting an IC50 of 11 nM. It is widely used in cancer research to investigate oncogenic signaling pathways, demonstrating antitumor activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
1801765-04-7
Product Name Alternative
Batoprotafib, BCS, Aberrant, allosteric, activation, CRC, Inhibitor, HNSCC, malignancy, EGFR-mutant, inhibit, NSCLC, TNO155, TNO-155, TNO 155, RTK-dependent, Phosphatase, SHP2, SHP-2
Field of Research
Metabolism Research
Purity
98.03% (May vary between batches)
Solubility
DMSO:50 mg/mL (118.5 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.92 mM)
Smiles
C[C@@H]1OCC2 (CCN (CC2) c2cnc (Sc3ccnc (N) c3Cl) c (N) n2) [C@@H]1N
Molecular Formula
C18H24ClN7OS
Molecular Weight
421.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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