TL02-59
TL02-59 is a potent and selective small-molecule inhibitor of the Src-family kinase Fgr (IC50 = 0.03 nM), with additional activity against Lyn and Hck. It demonstrates potent anti-proliferative effects in acute myelogenous leukemia (AML) cell cultures, supporting its use as a research tool for studying kinase signaling in hematological malignancies.
Product Specifications
CAS Number
1315330-17-6
Product Name Alternative
Acute, AML, Apoptosis, c-Fgr, orally, Lyn, Inhibitor, inhibit, myelogenous, Fgr, leukemia, Hck, TL02 59, TL0259, TL-02-59, TL02-59, Src
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
95.63% (May vary between batches)
Solubility
DMSO:120 mg/mL (196.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.56 mM)
Smiles
CCN1CCN (Cc2ccc (NC (=O) c3ccc (C) c (Oc4ncnc5cc (OC) c (OC) cc45) c3) cc2C (F) (F) F) CC1
Molecular Formula
C32H34F3N5O4
Molecular Weight
609.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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