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TP-10

TP-10 is a potent and selective phosphodiesterase 10A (PDE10A) inhibitor, exhibiting an IC50 of 0.8 nM. This small molecule is a valuable research tool for studying striatal signaling in neurological and psychiatric disorders, with applications in both in vitro enzymatic assays and in vivo models of conditions like schizophrenia and Huntington's disease.

Product Specifications

CAS Number

898563-00-3

Product Name Alternative

CAMP, disorder, cGMP, PDE10A, pCREB-LI, inhibit, Inhibitor, U-87 MG, schizophrenia, Phosphodiesterase (PDE), TP 10, TP10, TP-10, reactive oxygen

Field of Research

Metabolism Research

Purity

98.48% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.17 mM) ; DMSO:95 mg/mL (206.32 mM)

Smiles

FC (F) (F) Cn1cc (c (n1) -c1ccc (OCc2ccc3ccccc3n2) cc1) -c1ccncc1

Molecular Formula

C26H19F3N4O

Molecular Weight

460.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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