TP-10
TP-10 is a potent and selective phosphodiesterase 10A (PDE10A) inhibitor, exhibiting an IC50 of 0.8 nM. This small molecule is a valuable research tool for studying striatal signaling in neurological and psychiatric disorders, with applications in both in vitro enzymatic assays and in vivo models of conditions like schizophrenia and Huntington's disease.
Product Specifications
CAS Number
898563-00-3
Product Name Alternative
CAMP, disorder, cGMP, PDE10A, pCREB-LI, inhibit, Inhibitor, U-87 MG, schizophrenia, Phosphodiesterase (PDE), TP 10, TP10, TP-10, reactive oxygen
Field of Research
Metabolism Research
Purity
98.48% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.17 mM) ; DMSO:95 mg/mL (206.32 mM)
Smiles
FC (F) (F) Cn1cc (c (n1) -c1ccc (OCc2ccc3ccccc3n2) cc1) -c1ccncc1
Molecular Formula
C26H19F3N4O
Molecular Weight
460.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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