CSF1R-IN-2
CSF1R-IN-2 is a potent, orally bioavailable small molecule inhibitor targeting SRC, MET, and c-FMS (CSF1R) kinases with sub-nanomolar IC50 values. It serves as a valuable research tool for investigating tumor proliferation, metastasis, and tumor-associated macrophage biology in both cellular and animal models of cancer and inflammatory diseases.
Product Specifications
CAS Number
2271119-26-5
Product Name Alternative
C-Met/HGFR, cMet/HGFR, cMet, c-Met, colony stimulating factor 1 receptor, CSF1R IN 2, CSF1RIN2, CSF-1R-IN-2, CSF1R-IN-2, CSF-1R, CSF1R, CSF-1 receptor, cFms, c-FMS, c-Fms, inhibit, MET, HGFR, Inhibitor, Src, SRC
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.29% (May vary between batches)
Solubility
DMSO:25 mg/mL (61.06 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.88 mM)
Smiles
CCN1Cc2c (O[C@@H] (C) CNC (=O) c3c (N) nn4ccc1nc34) ccc (F) c2C#N
Molecular Formula
C20H20FN7O2
Molecular Weight
409.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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