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TRPV4 agonist-1 free base

TRPV4 agonist-1 free base (OUN67600) is a potent and selective small molecule agonist of the TRPV4 ion channel, demonstrating an EC50 of 60 nM in a human TRPV4 calcium influx assay. This compound is a valuable research tool for investigating TRPV4-mediated signaling in various physiological and pathological contexts, including studies of osmoregulation, pain, and inflammation in both cellular and animal models.

Product Specifications

CAS Number

2314467-59-7

Product Name Alternative

OUN 67600, OUN67600, OUN-67600, inhibit, Inhibitor, Transient receptor potential channels, TRPVChannel, TRPV Channel, TRPV4, TRPV4 agonist 1 free base, TRPV4 agonist-1, TRPV4 agonist1 free base, TRPV-4 agonist-1 free base, TRPV4 agonist-1 free base, TRP Channel, TRPChannel

Field of Research

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Purity

99.79% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (7.36 mM) ; DMSO:83.33 mg/mL (185.81 mM)

Smiles

CN1CCN (CC1) c1nc2c (F) cccc2c (=O) n1-c1ccc (Oc2ccc (F) cc2) cc1

Molecular Formula

C25H22F2N4O2

Molecular Weight

448.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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