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Trovafloxacin mesylate

Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits DNA gyrase and topoisomerase IV. It also specifically blocks the pannexin 1 (PANX1) channel with an IC50 of 4 μM. This dual activity makes it a useful research tool for studying bacterial replication and PANX1-mediated cellular signaling in vitro.

Product Specifications

CAS Number

147059-75-4

Product Name Alternative

Antibiotic, Bacterial, broad-spectrum, DNA, DNA Synthesis, DNASynthesis, DNA-gyrase, gyrase, Inhibitor, hepatotoxicity, NF-κB, LPS, PANX1, panx1, Pannexin 1 channel (PANX1), inhibit, pneumococci, TNF, Topo IV, Topoisomerase, topoisomerase-IV, pro-inflammatory, RNASynthesis, RNA Synthesis, TRPVChannel, TRPV Channel, TRPChannel, TRP Channel, Trovafloxacin, Trovafloxacin mesylate, Trovafloxacin Mesylate

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.12% (May vary between batches)

Solubility

DMSO:120 mg/mL (234.16 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.81 mM) ; H2O:18 mg/mL (35.12 mM)

Smiles

CS (O) (=O) =O.[H][C@@]12CN (C[C@]1 ([H]) [C@H]2N) c1nc2n (cc (C (O) =O) c (=O) c2cc1F) -c1ccc (F) cc1F

Molecular Formula

C21H19F3N4O6S

Molecular Weight

512.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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