Tyrphostin AG1433
Tyrphostin AG1433 is a dual inhibitor of the PDGFRβ and VEGFR-2 (KDR) tyrosine kinases with IC50 values of 5.0 μM and 9.3 μM, respectively. This compound is used in biochemical and cellular research to study angiogenesis and tumor growth pathways in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
168835-90-3
Product Name Alternative
Cytotoxicity, AG 1433, AG1433, AG-1433, angiogenesis, tyrosine, ATM, Flk1, Flk-1, Inhibitor, inhibit, KDR, kinases, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, SU 1433, SU1433, SU-1433, Vascular endothelial growth factor receptor, VEGFR, VEGFR2, VEGFR-2, Tyrphostin AG 1433, Tyrphostin AG1433, Tyrphostin AG-1433
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.51% (May vary between batches)
Solubility
DMSO:3.06 mg/mL (11.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.76 mM)
Smiles
Cc1cc2ncc (nc2cc1C) -c1ccc (O) c (O) c1
Molecular Formula
C16H14N2O2
Molecular Weight
266.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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