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Tyrphostin AG1433

Tyrphostin AG1433 is a dual inhibitor of the PDGFRβ and VEGFR-2 (KDR) tyrosine kinases with IC50 values of 5.0 μM and 9.3 μM, respectively. This compound is used in biochemical and cellular research to study angiogenesis and tumor growth pathways in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

168835-90-3

Product Name Alternative

Cytotoxicity, AG 1433, AG1433, AG-1433, angiogenesis, tyrosine, ATM, Flk1, Flk-1, Inhibitor, inhibit, KDR, kinases, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, SU 1433, SU1433, SU-1433, Vascular endothelial growth factor receptor, VEGFR, VEGFR2, VEGFR-2, Tyrphostin AG 1433, Tyrphostin AG1433, Tyrphostin AG-1433

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.51% (May vary between batches)

Solubility

DMSO:3.06 mg/mL (11.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.76 mM)

Smiles

Cc1cc2ncc (nc2cc1C) -c1ccc (O) c (O) c1

Molecular Formula

C16H14N2O2

Molecular Weight

266.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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