Ubiquitination-IN-1
Ubiquitination-IN-1 is a potent small molecule inhibitor that disrupts the Cks1-Skp2 interaction and inhibits ubiquitination with an IC50 of 0.17 μM. This compound is a valuable research tool for studying cell cycle regulation, protein degradation, and has been utilized in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
1819330-15-8
Product Name Alternative
Inhibit, Inhibitor, interaction, E1 activating enzyme, E2 conjugating enzyme, E1/E2/E3 Enzyme, E3 ligating enzyme, degradation, Cksl, protein-protein, Skp2, suppressors, tumor, Ubiquitin activating enzyme, ubiquitination, Ubiquitination IN 1, UbiquitinationIN1, Ubiquitination-IN-1, Ubiquitin ligase, Ubiquitin conjugating enzyme
Field of Research
Protein Biochemistry
Purity
98.36% (May vary between batches)
Solubility
DMSO:60 mg/mL (139.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)
Smiles
FC (F) (F) c1cccc (c1) S (=O) (=O) Nc1ccc (-c2cccnc2) c2cccnc12
Molecular Formula
C21H14F3N3O2S
Molecular Weight
429.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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