Nortriptyline HCl
Nortriptyline hydrochloride is the active N-demethylated metabolite of amitriptyline, functioning as a tricyclic antidepressant. It is utilized in research models of major depressive disorder and dysthymia to investigate its mechanisms in neurotransmitter reuptake inhibition, employing both in vitro binding assays and in vivo behavioral studies.
Product Specifications
CAS Number
894-71-3
Product Name Alternative
Depression, Desitriptilina, Desitriptyline HCl, Desmethylamitriptyline, Desmethylamitriptyline Hydrochloride, Desmethylamitriptyline hydrochloride, Dopamine, Dopamine Receptor, Drug Metabolite, DopamineReceptor, DrugMetabolite, 5-HT, 5HT Receptor, 5HTReceptor, Adrenergic Receptor, AdrenergicReceptor, Autophagy, Apoptosis, Inhibitor, Histamine Receptor, HistamineReceptor, H1 receptor, ELF 101 Hydrochloride, ELF101 Hydrochloride, ELF-101 hydrochloride, ELF-101 Hydrochloride, EN-7048 Hydrochloride, EN-7048 hydrochloride, EN7048 Hydrochloride, EN 7048 Hydrochloride, metabolite, mAChR, inhibit, Noradrenaline transporter (Sodium-dependent), Nortriptyline, Nortriptyline Hydrochloride, Nortriptyline hydrochloride, Sert (Sodium-dependent), tumor, tricyclic antidepressant
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Antidepressant; Mitochondrial PTP inhibitor
Form
Powder
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.67 mM) ; Ethanol:54 mg/mL (180.1 mM)
Smiles
Cl.CNCC\C=C1\c2ccccc2CCc2ccccc12
Molecular Formula
C19H22ClN
Molecular Weight
299.84
Storage Conditions
-20°C
Notes
For research use only.
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