UT-34
UT-34 is a potent, orally bioavailable pan-androgen receptor antagonist and degrader effective against wild-type and mutant (F876L, W741L) AR. It demonstrates anti-tumor activity in prostate cancer models, making it a valuable research tool for investigating AR signaling and therapeutic resistance in both in vitro and in vivo studies.
Product Specifications
CAS Number
2168525-92-4
Product Name Alternative
Degrader, cancer, ARVs, AndrogenReceptor, Androgen Receptor, androgen receptor, FKBP5, F876L AR, function-1, enzalutamide, ligand-binding, Inhibitor, inhibit, ubiquitin, UT 34, UT34, UT-34, W741L AR, proteasome, prostate, Wild-type AR
Field of Research
Metabolism Research
Purity
98.10% (May vary between batches)
Solubility
DMSO:71 mg/mL (199.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.61 mM)
Smiles
C[C@] (O) (Cn1cc (F) cn1) C (=O) Nc1ccc (C#N) c (c1) C (F) (F) F
Molecular Formula
C15H12F4N4O2
Molecular Weight
356.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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