VU591 hydrochloride
VU591 hydrochloride is a potent and selective antagonist of the renal outer medullary potassium channel (Kir1.1/ROMK), with an IC50 of 0.24 μM. It is a valuable research tool for studying renal physiology, hypertension, and diuretic mechanisms in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1315380-70-1
Product Name Alternative
Inhibitor, inhibit, KcsA, Kir1.1, neurological, ROMK, ROMK channel, ROMK Inhibitor, Potassium Channel, PotassiumChannel, VU 591, VU 591 Hydrochloride, VU591, VU-591, VU591 hydrochloride, VU591 Hydrochloride, VU-591 Hydrochloride, VU-591 hydrochloride
Field of Research
Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:4.33 mg/mL (10.7 mM)
Smiles
Cl.[O-][N+] (=O) c1ccc2nc (COCc3nc4ccc (cc4[nH]3) [N+] ([O-]) =O) [nH]c2c1
Molecular Formula
C16H13ClN6O5
Molecular Weight
404.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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