VU6005649
VU6005649 is a centrally penetrant small molecule agonist for the mGlu7 and mGlu8 receptors, exhibiting EC50 values of 0.65 μM and 2.6 μM, respectively. This compound is a valuable research tool for investigating the role of these receptors in neurological and psychiatric disorders, supporting both in vitro binding studies and in vivo behavioral experiments.
Product Specifications
CAS Number
2137047-43-7
Product Name Alternative
Inhibit, Metabotropic glutamate receptors, mGlu7, mGlu7 receptor, mGlu8, mGlu8 receptor, mGluR, Inhibitor, VU 6005649, VU6005649, VU-6005649
Field of Research
Neuroscience
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.6 mM) ; DMSO:60 mg/mL (167.94 mM)
Smiles
COc1ccc (-c2c (C) nn3c (cc (C) nc23) C (F) (F) F) c (F) c1F
Molecular Formula
C16H12F5N3O
Molecular Weight
357.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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