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VU6005649

VU6005649 is a centrally penetrant small molecule agonist for the mGlu7 and mGlu8 receptors, exhibiting EC50 values of 0.65 μM and 2.6 μM, respectively. This compound is a valuable research tool for investigating the role of these receptors in neurological and psychiatric disorders, supporting both in vitro binding studies and in vivo behavioral experiments.

Product Specifications

CAS Number

2137047-43-7

Product Name Alternative

Inhibit, Metabotropic glutamate receptors, mGlu7, mGlu7 receptor, mGlu8, mGlu8 receptor, mGluR, Inhibitor, VU 6005649, VU6005649, VU-6005649

Field of Research

Neuroscience

Purity

99.79% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.6 mM) ; DMSO:60 mg/mL (167.94 mM)

Smiles

COc1ccc (-c2c (C) nn3c (cc (C) nc23) C (F) (F) F) c (F) c1F

Molecular Formula

C16H12F5N3O

Molecular Weight

357.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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