VU 0365114
VU 0365114 is a selective positive allosteric modulator of the muscarinic acetylcholine receptor M5 (CHRM5), potentiating acetylcholine-induced calcium mobilization with an EC50 of 2.7 μM. This small molecule is a valuable research tool for investigating M5 receptor function in neuropharmacology, utilized in both in vitro signaling assays and in vivo studies of central nervous system pathways.
Product Specifications
CAS Number
1208222-39-2
Product Name Alternative
M5 mAChR, mAChR, mAChR M5, inhibit, Muscarinic acetylcholine receptor, Inhibitor, VU 0365114, VU0365114, VU-0365114
Field of Research
Neuroscience
Purity
97.29% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:45 mg/mL (113.25 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)
Smiles
FC (F) (F) Oc1ccc2N (Cc3ccc (cc3) -c3ccccc3) C (=O) C (=O) c2c1
Molecular Formula
C22H14F3NO3
Molecular Weight
397.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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