WAY-213613 hydrochloride
WAY-213613 hydrochloride is a potent and selective nonsubstrate inhibitor of the glutamate transporter EAAT2 (GLT-1), with an IC50 of 85 nM. It exhibits over 40-fold selectivity versus EAAT1 and EAAT3 and is inactive at glutamate receptors. This compound serves as a valuable pharmacological tool for studying EAAT2 function in both in vitro and in vivo models of CNS disorders.
Product Specifications
CAS Number
2450268-84-3
Product Name Alternative
868359-05-1, 868359-05-1 free base, Human EAAT1, Human EAAT2, Human EAAT3, WAY 213613 Hydrochloride, WAY 213613 hydrochloride, WAY-213613 hydrochloride (868359-05-1 free base), WAY213613 Hydrochloride, WAY213613 hydrochloride, WAY-213613 Hydrochloride
Field of Research
Metabolism Research
Purity
98.99% (May vary between batches)
Solubility
DMSO:55 mg/mL (132.47 mM) ; H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.82 mM)
Smiles
N[C@@H] (CC (Nc (cc1) ccc1Oc (cc (c (F) c1) F) c1Br) =O) C (O) =O
Molecular Formula
C16H13BrF2N2O4
Molecular Weight
415.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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