WS-383
WS-383 is a potent and selective small molecule inhibitor of the DCN1-UBC12 protein-protein interaction, exhibiting reversible binding with an IC50 of 11 nM. It serves as a valuable chemical probe for studying cullin neddylation in biochemical and cellular assays, with utility in cancer and developmental biology research.
Product Specifications
CAS Number
2247544-02-9
Product Name Alternative
Cell, DCN1-UBC12, DCN1-UBC12 interaction, E2Enzyme, E3 Enzyme, E2 Enzyme, E2 conjugating enzyme, E1Enzyme, E1 activating enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E3 ligating enzyme, E3Enzyme, Inhibitor, interaction, KYSE70, inhibit, MGC-803, WS383, WS-383, WS 383, Ubiquitin ligase, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme
Field of Research
Protein Biochemistry
Purity
98.46% (May vary between batches)
Solubility
DMSO:6.5 mg/mL (13.04 mM)
Smiles
Cl.CN (C) CCn1nnnc1Sc1cc (C) nc2nc (SCc3ccc (Cl) cc3) nn12
Molecular Formula
C18H21Cl2N9S2
Molecular Weight
498.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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