Zamicastat
Zamicastat is a dopamine β-hydroxylase (DBH) inhibitor that also acts as a dual inhibitor of the efflux transporters P-gp and BCRP. This small molecule is used in research to study catecholamine regulation and transporter interactions in both cellular and animal models of cardiovascular and neurological diseases.
Product Specifications
CAS Number
1080028-80-3
Product Name Alternative
Zamicastat, P-gp, P-gp (P-glycoprotein), Pgp, P-glycoprotein, Cluster of differentiation 243, CD243, Breast cancer resistance protein, Dopamine beta-monooxygenase, Dopamine beta-hydroxylase, Dopamine β-hydroxylase, Dopamine β-monooxygenase, ABCB1, ABCG2, BIA 5-1058, BCRP, Inhibitor, Multidrug resistance protein 1, inhibit, MDR1
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
97.43% (May vary between batches)
Solubility
DMSO:150 mg/mL (373.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.96 mM)
Smiles
Fc1cc (F) c2OC[C@@H] (Cc2c1) n1c (CCNCc2ccccc2) c[nH]c1=S
Molecular Formula
C21H21F2N3OS
Molecular Weight
401.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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