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ZK824190

ZK824190 is a selective, orally bioavailable small molecule inhibitor of urokinase plasminogen activator (uPA), demonstrating selectivity over tissue-type plasminogen activator and plasmin. It is a research tool for studying uPA's role in cancer cell invasion, metastasis, and angiogenesis in both in vitro and in vivo models.

Product Specifications

CAS Number

2254001-81-3

Product Name Alternative

Inhibit, multiple sclerosis, PAI-1, Inhibitor, Serine proteases, Serine Protease, Serine, Serine endopeptidases, Ser/Thr Protease, Threonine proteases, SerineProtease, Plasminogen activator inhibitor-1, Plasmin, plasminogen, ZK824190, ZK-824190, ZK 824190, protease, tPA, uPA, Urokinase

Field of Research

Metabolism Research, Protein Biochemistry

Purity

98.84% (May vary between batches)

Solubility

DMSO:12 mg/mL (28.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.83 mM)

Smiles

O (C=1C=C (C=CC1) C2=CC (CN) =CC=C2) C=3N=C (O[C@@H] (C (O) =O) CC) C (F) =CC3F

Molecular Formula

C22H20F2N2O4

Molecular Weight

414.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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