(R) -ADX-47273
(R) -ADX-47273 is a selective positive allosteric modulator of the mGlu5 receptor, exhibiting an EC50 of 168 nM. It is a valuable research tool for investigating the role of mGlu5 in neurological disorders, with utility in both in vitro assays and in vivo preclinical models.
Product Specifications
CAS Number
851881-59-9
Product Name Alternative
ADX47273, ADX-47273, ADX 47273, (R) ADX 47273, (R) ADX47273, inhibit, Inhibitor, mGlu5, mGluR, mGluR5, Metabotropic glutamate receptors
Field of Research
Metabolism Research, Neuroscience
Purity
99.87% (May vary between batches)
Solubility
DMSO:95 mg/mL (257.2 mM)
Smiles
Fc1ccc (cc1) C (=O) N1CCC[C@H] (C1) c1nc (no1) -c1ccc (F) cc1
Molecular Formula
C20H17F2N3O2
Molecular Weight
369.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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