Afoxolaner
Afoxolaner is an isoxazoline-class ectoparasiticide that targets GABA and glutamate-gated chloride channels in arthropods, leading to uncontrolled neuronal excitation and death. It is widely used in veterinary research for in vivo efficacy studies against ticks like Ixodes scapularis in dogs and for in vitro investigations of insecticide mode of action.
Product Specifications
CAS Number
1093861-60-9
Product Name Alternative
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.10% (May vary between batches)
Solubility
DMSO:≥ 250 mg/mL (399.44 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.2 mM)
Smiles
FC (F) (F) CNC (=O) CNC (=O) c1ccc (C2=NOC (C2) (c2cc (Cl) cc (c2) C (F) (F) F) C (F) (F) F) c2ccccc12
Molecular Formula
C26H17ClF9N3O3
Molecular Weight
625.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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