AZ7550 hydrochloride
AZ7550 hydrochloride is the active metabolite of AZD9291 (Osimertinib) and acts as an IGF1R inhibitor with an IC50 of 1.6 μM. This small molecule is a valuable research tool for studying IGF-1R signaling in cancer models, applicable in both in vitro biochemical assays and in vivo preclinical research.
Product Specifications
CAS Number
2309762-40-9
Product Name Alternative
PYK2, Txk, TEC, Ins R, Inhibitor, HER1, FLT4, IGF-1R, IGF1R, FLT3, FES, FAK, ErbB4, ErbB-1, EGFR, Epidermal growth factor receptor, IRR, inhibit, MNK2, MLK1, AZ7550, AZ-7550, AZ7550 hydrochloride, AZ7550 Hydrochloride, AZ-7550 Hydrochloride, AZ-7550 hydrochloride, AZ7550 hydrochloride (1421373-99-0 free base), AZ 7550, AZ 7550 Hydrochloride, BLK, BTK, 1421373-99-0, 1421373-99-0 free base, ACK1, ALK, BRK, Drug Metabolite
Field of Research
Cardiovascular Research, Metabolism Research, Signal Transduction
Purity
97.07% (May vary between batches)
Solubility
DMSO:1.5 mg/mL (2.87 mM)
Smiles
C=CC (NC1=CC (NC2=NC=CC (C3=CN (C4=C3C=CC=C4) C) =N2) =C (C=C1N (CCNC) C) OC) =O.[H]Cl
Molecular Formula
C27H32ClN7O2
Molecular Weight
522.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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