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ChX710

ChX710 is a small molecule activator of the cytosolic DNA-sensing pathway. It triggers the type I interferon response by promoting IRF3 phosphorylation and priming specific Interferon-Stimulated Genes (ISGs) . This tool compound is valuable for studying antiviral immunity and autoimmune disorders in both cellular and animal models.

Product Specifications

CAS Number

2438721-44-7

Product Name Alternative

ChX 710, ChX710, ChX-710, Inhibitor, ERIS, MITA, MPYS, inhibit, TMEM173, Stimulator of Interferon Genes, STING

Field of Research

Immunology & Inflammation

Purity

99.51% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (3.09 mM) ; DMSO:60 mg/mL (185.53 mM)

Smiles

CC (CN (C) C) NC (=O) c1cccc2nc ([nH]c12) -c1ccncc1

Molecular Formula

C18H21N5O

Molecular Weight

323.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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