L-2-Hydroxyglutaric acid disodium
L-2-Hydroxyglutaric acid disodium salt is an oncometabolite and epigenetic modifier implicated in renal cancer. It acts as a competitive inhibitor of mitochondrial creatine kinase (Mi-CK), with reported Km and Ki values of 2.52 mM and 11.13 mM, respectively. This compound is utilized in cancer metabolism research to study its roles in vitro and in vivo.
Product Specifications
CAS Number
63512-50-5
Product Name Alternative
Inhibit, L 2 Hydroxyglutaric acid disodium, methylation, modifier, MitochondrialMetabolism, Mitochondrial Metabolism, Inhibitor, L-2-Hydroxyglutaric acid, L2Hydroxyglutaric acid disodium, L-2-Hydroxyglutaric acid disodium, HistoneDemethylase, histone, Histone Demethylase, epigenetic, demethylases, (S) -2-Hydroxyglutaric acid disodium, 2-Hydroxyglutaric acid, 2-Hydroxyglutaric acid disodium, cancer, renal
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
95.00% (May vary between batches)
Solubility
H2O:100 mg/mL (520.62 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
[Na+].[Na+].O[C@@H] (CCC ([O-]) =O) C ([O-]) =O
Molecular Formula
C5H6Na2O5
Molecular Weight
192.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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