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UCB-9260

UCB-9260 is a small molecule inhibitor that attenuates TNF signaling by stabilizing an asymmetric conformation of the TNF trimer. This mechanism makes it a valuable research tool for studying TNF-mediated inflammation in both cellular and animal models of autoimmune and inflammatory diseases.

Product Specifications

CAS Number

1515888-53-5

Product Name Alternative

Tumor Necrosis Factor Receptor, trimer, UCB 9260, UCB9260, UCB-9260, selective, TNFR, TNF, TNF Receptor, rheumatoid, arthritis, asymmetric, autoimmune, cytotoxicity, cytokine, inhibit, Inhibitor, neutrophil

Field of Research

Cell Biology

Purity

98.39% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.81 mM) ; DMSO:81.7 mg/mL (192.91 mM)

Smiles

Cc1ccc (C) c (Cn2c (nc3ccc (cc23) -c2cnn (C) c2) C (O) c2ccncc2) c1

Molecular Formula

C26H25N5O

Molecular Weight

423.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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