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ZL0580

ZL0580 is a research compound that suppresses HIV replication through a multi-faceted mechanism. It inhibits Tat-mediated transactivation and transcription elongation while promoting a repressive chromatin state at the viral promoter. This small molecule is a useful tool for studying HIV latency reversal and transcriptional control in both cellular and biochemical assays.

Product Specifications

CAS Number

2377151-10-3

Product Name Alternative

BRD4, PBMC, inhibit, Inhibitor, low, HIV, HIV Protease, HIVProtease, Human immunodeficiency virus, Epigenetic Reader Domain, EpigeneticReaderDomain, toxicity, ZL 0580, ZL0580, ZL-0580

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Protein Biochemistry

Purity

99.70% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.39 mM) ; DMSO:250 mg/mL (469.46 mM)

Smiles

FC (F) (F) c1ccc (NC (=O) Nc2ccc (cc2) S (=O) (=O) N2CCC[C@H]2C (=O) Nc2ccccc2) cc1

Molecular Formula

C25H23F3N4O4S

Molecular Weight

532.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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