4E2RCat
4E2RCat is a small molecule inhibitor of the eIF4E-eIF4G interaction with an IC50 of 13.5 μM. It effectively suppresses coronavirus replication by reducing viral protein synthesis and the yield of infectious virus, making it a useful tool for studying cap-dependent translation and antiviral mechanisms in vitro.
Product Specifications
CAS Number
432499-63-3
Product Name Alternative
Virus Protease, 4E2RCat, 4E-2RCat, Autophagy, Inhibitor, eIF4E-Eif4g, eIF4E-eIF4G, Eukaryotic Initiation Factor (eIF), inhibit
Field of Research
Cell Biology, Infectious Disease & Virology
Purity
96.48% (May vary between batches)
Solubility
DMSO:15.5 mg/mL (34 mM)
Smiles
OC (=O) c1cc (ccc1Cl) -c1ccc (\C=C2/SC (=S) N (Cc3ccccc3) C2=O) o1
Molecular Formula
C22H14ClNO4S2
Molecular Weight
455.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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