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A-3 hydrochloride

A-3 hydrochloride is a cell-permeable, ATP-competitive kinase antagonist with broad selectivity. It potently inhibits PKA, CKII, and MLCK, and also blocks PKC and casein kinase I. This compound is a valuable research tool for studying kinase signaling pathways in both cellular and biochemical assays.

Product Specifications

CAS Number

78957-85-4

Product Name Alternative

MLC-kinase, kinase, inhibit, inhibitor, A 3, A 3 hydrochloride, A 3 Hydrochloride, A-3, A3 Hydrochloride, A3 hydrochloride, A-3 Hydrochloride, cAMP, CaMK, calmodulin, Calmodulin-dependent kinases, Calmodulin-dependent protein kinases, casein, CaseinKinase, Casein Kinase, CK1, CK2, PKA, PKC, Protein kinase A, Protein kinase C

Field of Research

Epigenetics & Chromatin, Metabolism Research, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.32% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.45 mM) ; DMSO:125 mg/mL (389.14 mM)

Smiles

Cl.NCCNS (=O) (=O) c1cccc2c (Cl) cccc12

Molecular Formula

C12H14Cl2N2O2S

Molecular Weight

321.22

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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