A-443654
A-443654 is a potent pan-Akt inhibitor with equipotent activity against Akt1, Akt2, and Akt3 isoforms, exhibiting a cellular Ki of 160 pM. This compound is widely used in biochemical and cellular research to investigate the PI3K/Akt signaling pathway in cancer and metabolic studies, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
552325-16-3
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.73% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.06 mM) ; DMSO:100 mg/mL (251.59 mM)
Smiles
C ([C@@H] (COC=1C=C (C=NC1) C=2C=C3C (=CC2) NN=C3C) N) C=4C=5C (NC4) =CC=CC5
Molecular Formula
C24H23N5O
Molecular Weight
397.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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