A-485
A-485 is a potent and selective small molecule inhibitor of the p300 and CBP histone acetyltransferases, with IC50 values of 9.8 nM and 2.6 nM, respectively. It has demonstrated antitumor activity in preclinical studies, including models of hematologic cancers and androgen receptor-positive prostate cancer, in both cellular and animal experiments.
Product Specifications
CAS Number
1889279-16-6
Product Name Alternative
CBP, CBP/p300, A485, A-485, A 485, Inhibitor, histone acetyltransferase, Histone Acetyltransferase, HistoneAcetyltransferase, HAT, HATs, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, p300
Field of Research
Epigenetics & Chromatin
Purity
98.01% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.32 mM) ; DMSO:252.5 mg/mL (470.66 mM)
Smiles
CNC (=O) Nc1ccc2c (CC[C@@]22OC (=O) N (CC (=O) N (Cc3ccc (F) cc3) [C@@H] (C) C (F) (F) F) C2=O) c1
Molecular Formula
C25H24F4N4O5
Molecular Weight
536.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
G8583-01-PE 200 µL
GPLD1, CT (Phosphatidylinositol-glycan-specific Phospholipase D, PI-G PLD, Glycoprotein Phospholipase D, Glycosyl-phosphatidylinositol-specific Phospholipase D, GPI-specific Phospholipase D, GPI-PLD, PIGPLD1) (PE) discontinued
Sign In for Pricing
View Details ![Mouse Monoclonal Talin1 Antibody (TA205) [DyLight 550]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP1-21642R 0.1 mL
Mouse Monoclonal Talin1 Antibody (TA205) [DyLight 550]
Sign In for Pricing
View Details 
