Compound 147 (AA147)
AA147 is a prodrug that selectively activates the ATF6 branch of the unfolded protein response via localized metabolic activation and covalent modification of ER proteins. It is used in research to study ER proteostasis in models of neurodegenerative and metabolic diseases, both in vitro and in vivo.
Product Specifications
CAS Number
393121-74-9
Product Name Alternative
Neurodegenerative disorders, NRF2, inhibit, Inhibitor, AA147, AA-147, AA 147, BPAEC, ATF6, ATF6-activator-147, ROS, SMA
Field of Research
Cell Biology, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
ATF6 activator; ER proteostasis
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Smiles
Cc1ccc (O) c (NC (=O) CCc2ccccc2) c1
Molecular Formula
C16H17NO2
Molecular Weight
255.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (2-hydroxy-5-methylphenyl) -3-phenylpropanamide
Available Sizes
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