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Torsemide

Torsemide (AC-4464) is a loop diuretic of the anilinopyridine sulfonylurea class, characterized by its extended plasma half-life, prolonged action, and high protein binding. It is widely used in research models of hypertension, heart failure, and edema to investigate renal sodium-potassium-chloride cotransporter inhibition in both in vivo and in vitro systems.

Product Specifications

CAS Number

56211-40-6

Product Name Alternative

AC 4464, AC4464, AC-4464, anti-aldosterone, diuretic, disease, cirrhosis, failure, hepatic, heart, JDL 464, JDL464, JDL-464, inhibit, Inhibitor, NaKCl cotransporter, Na-K-Cl cotransporter, NaKClcotransporter, vasodilatory, Torsemide, Torasemide, renal

Field of Research

Pharmacology & Drug Discovery

Purity

99.81% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (64.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.87 mM)

Smiles

CC (C) NC (=O) NS (=O) (=O) C1=C (NC2=CC=CC (C) =C2) C=CN=C1

Molecular Formula

C16H20N4O3S

Molecular Weight

348.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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