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ACT-678689

ACT-678689 is a potent and selective tryptophan hydroxylase (TPH) inhibitor, exhibiting an IC50 of 8 nM. This compound is a valuable research tool for investigating serotonin biosynthesis in both cellular and animal models, supporting studies in neuropharmacology and related metabolic pathways.

Product Specifications

CAS Number

1783256-96-1

Product Name Alternative

Compound Example 1.53.4, ACT678689, ACT-678689, ACT 678689, Inhibitor, inhibit, Tryptophan Hydroxylase, Tryptophan hydroxylase, TPH

Field of Research

Metabolism Research

Purity

99.45% (May vary between batches)

Solubility

DMSO:120 mg/mL (212.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.08 mM)

Smiles

C (COC1=C (Cl) N=C (NS (C) (=O) =O) C=C1) (=O) N2[C@H] (C=3N4C (=NC3CC2) SC (C) =N4) C5=C (F) C=C (C) C=C5

Molecular Formula

C23H22ClFN6O4S2

Molecular Weight

565.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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