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AG 1295

AG 1295 is a potent and selective small molecule inhibitor of the platelet-derived growth factor receptor (PDGFR) tyrosine kinase. It specifically blocks PDGFR autophosphorylation while sparing the EGF receptor, making it a valuable tool for studying PDGF signaling in cancer research and cellular proliferation assays both in vitro and in vivo.

Product Specifications

CAS Number

71897-07-9

Product Name Alternative

Inhibitor, inhibit, Platelet-derived growth factor receptor, PDGFR, autophosphorylation, AG1295, AG-1295, AG 1295, RTK, PDGF-receptor

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.64% (May vary between batches)

Solubility

DMSO:60 mg/mL (256.08 mM)

Smiles

Cc1cc2ncc (nc2cc1C) -c1ccccc1

Molecular Formula

C16H14N2

Molecular Weight

234.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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