Gemfibrozil
Gemfibrozil is a PPARα agonist that promotes fatty acid oxidation and lipoprotein lipase synthesis, enhancing triglyceride clearance and reducing apoC-III and VLDL-C. It also increases apoA-I/A-II expression to raise HDL-C. This fibric acid derivative is used in research on dyslipidemia, atherosclerosis, and metabolic syndrome in both cellular and animal models.
Product Specifications
CAS Number
25812-30-0
Product Name Alternative
Lopid, inhibit, Jezil, Gemfibrozil, Inhibitor, CI 719, CI719, CI-719, Decrelip, Cytochrome P450, CYPs, CYP1A2, CYP2C9, AdrenergicReceptor, Adrenergic Receptor, Peroxisome proliferator-activated receptors, PPAR, PPARα
Field of Research
Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
98.59% (May vary between batches)
Solubility
DMSO:250 mg/mL (998.68 mM) ; Ethanol:47 mg/mL (187.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.99 mM)
Smiles
CC1=CC (OCCCC (C) (C) C (O) =O) =C (C) C=C1
Molecular Formula
C15H22O3
Molecular Weight
250.33
Storage Conditions
-20°C
Notes
For research use only.
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