Aldose reductase-IN-1
Aldose reductase-IN-1 (AT-001, Caficrestat) is a picomolar-potency aldose reductase inhibitor (IC50 = 28.9 pM) . It has been investigated for targeting the relaxin signaling pathway in prostate cancer models, showing relevance for in vitro and in vivo oncological research.
Product Specifications
CAS Number
1355612-71-3
Product Name Alternative
Inhibit, Inhibitor, Aldose Reductase, Aldose reductase IN 1, Aldose reductaseIN1, Aldose reductase-IN-1, AT001, AT-001, AT 001, Caficrestat
Field of Research
Metabolism Research
Purity
99.56% (May vary between batches)
Solubility
DMSO:45 mg/mL (106.8 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.75 mM)
Smiles
OC (=O) Cc1nn (Cc2nc3cc (ccc3s2) C (F) (F) F) c (=O) c2nccnc12
Molecular Formula
C17H10F3N5O3S
Molecular Weight
421.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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