Ciliobrevin D
Ciliobrevin D is a cell-permeable small molecule inhibitor of the AAA+ ATPase motor protein cytoplasmic dynein. It is widely used in research to disrupt dynein-dependent processes, including Hedgehog signaling and primary cilia formation in vivo, as well as microtubule motility and ATPase activity in vitro.
Product Specifications
CAS Number
1370554-01-0
Product Name Alternative
Hedgehog, melanosome, Inhibitor, inhibit, Ciliobrevin D, cytoplasmic, Cytoplasmic dynein, dynein, ATPases, ATPase, aggregation, peroxisomes, spindles, Smoothened, γ-tubulin
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.09% (May vary between batches)
Solubility
DMSO:9.23 mg/mL (23.51 mM)
Smiles
Clc1ccc (C (=O) C (\C#N) =C2/NC (=O) c3ccc (Cl) cc3N2) c (Cl) c1
Molecular Formula
C17H8Cl3N3O2
Molecular Weight
392.62
Storage Conditions
-20°C
Notes
For research use only.
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