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Ciliobrevin D

Ciliobrevin D is a cell-permeable small molecule inhibitor of the AAA+ ATPase motor protein cytoplasmic dynein. It is widely used in research to disrupt dynein-dependent processes, including Hedgehog signaling and primary cilia formation in vivo, as well as microtubule motility and ATPase activity in vitro.

Product Specifications

CAS Number

1370554-01-0

Product Name Alternative

Hedgehog, melanosome, Inhibitor, inhibit, Ciliobrevin D, cytoplasmic, Cytoplasmic dynein, dynein, ATPases, ATPase, aggregation, peroxisomes, spindles, Smoothened, γ-tubulin

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

98.09% (May vary between batches)

Solubility

DMSO:9.23 mg/mL (23.51 mM)

Smiles

Clc1ccc (C (=O) C (\C#N) =C2/NC (=O) c3ccc (Cl) cc3N2) c (Cl) c1

Molecular Formula

C17H8Cl3N3O2

Molecular Weight

392.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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