CJ-42794
CJ-42794 is a potent and selective antagonist of the human prostaglandin E receptor EP4, exhibiting a pKi of 8.5 and over 200-fold selectivity versus other EP subtypes. This tool compound is used in both in vitro and in vivo research to investigate EP4-mediated pathways in inflammation, cancer, and pain.
Product Specifications
CAS Number
847728-01-2
Product Name Alternative
Progesterone Receptor, prostaglandin E2, tumor necrosis factor α, human whole blood, Inhibitor, gastric ulcers, inhibit, NR3C3, CJ42794, CJ-42794, CJ 042794, CJ 42794, CJ042794, CJ-042794, cAMP
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
99.49% (May vary between batches)
Solubility
DMSO:28 mg/mL (67.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.83 mM)
Smiles
C[C@H] (NC (=O) c1cc (Cl) ccc1Oc1ccc (F) cc1) c1ccc (cc1) C (O) =O
Molecular Formula
C22H17ClFNO4
Molecular Weight
413.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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