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CJ-42794

CJ-42794 is a potent and selective antagonist of the human prostaglandin E receptor EP4, exhibiting a pKi of 8.5 and over 200-fold selectivity versus other EP subtypes. This tool compound is used in both in vitro and in vivo research to investigate EP4-mediated pathways in inflammation, cancer, and pain.

Product Specifications

CAS Number

847728-01-2

Product Name Alternative

Progesterone Receptor, prostaglandin E2, tumor necrosis factor α, human whole blood, Inhibitor, gastric ulcers, inhibit, NR3C3, CJ42794, CJ-42794, CJ 042794, CJ 42794, CJ042794, CJ-042794, cAMP

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

99.49% (May vary between batches)

Solubility

DMSO:28 mg/mL (67.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.83 mM)

Smiles

C[C@H] (NC (=O) c1cc (Cl) ccc1Oc1ccc (F) cc1) c1ccc (cc1) C (O) =O

Molecular Formula

C22H17ClFNO4

Molecular Weight

413.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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