CLK-IN-T3
CLK-IN-T3 is a potent and selective small molecule inhibitor of CLK1, CLK2, and CLK3 kinases, with respective IC50 values of 0.67 nM, 15 nM, and 110 nM. It is a valuable research tool for studying CLK kinase biology and has demonstrated anti-proliferative effects in various cancer cell lines in vitro.
Product Specifications
CAS Number
2109805-56-1
Product Name Alternative
Inhibitor, inhibit, kinase, CDC-like, CDK, CLK IN T3, CLK, CLK1, CLK2, CLK3, CLKINT3, CLK-IN-T3, CLK-IN-T-3, Cyclin dependent kinase, Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, DYRK1A, DYRK1B, DYRK, anti-cancer, activity, stable
Field of Research
Cell Biology, Signal Transduction
Purity
98.37% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.07 mM) ; DMSO:4.5 mg/mL (9.32 mM)
Smiles
CN1CCN (CC1) C (=O) C (C) (C) c1ccc (cc1) C (=O) Nc1cn2cc (ccc2n1) -c1ccncc1
Molecular Formula
C28H30N6O2
Molecular Weight
482.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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