CMS-121
CMS-121 is an orally bioavailable quinolone derivative and potent acetyl-CoA carboxylase 1 (ACC1) inhibitor. It demonstrates neuroprotective, antioxidative, and anti-inflammatory properties, protecting HT22 cells from oxidative and ischemic damage with EC50 values of 7 nM and 200 nM, respectively, and shows renoprotective potential in research models.
Product Specifications
CAS Number
1353224-53-9
Product Name Alternative
Neuroprotective, mitochondrial, inhibit, Inhibitor, H3K9, dementia, disease, CMS121, CMS-121, CMS 121, ACC1, ACC, Acetyl Coenzyme A Carboxylase, Acetyl-CoA Carboxylase, AcetylCoA Carboxylase, acetylation, Acetyl-CoA carboxylase 1 (ACC1), AcetylCoACarboxylase, Alzheimer's, antioxidative, anti-inflammatory
Field of Research
Metabolism Research
Purity
98.71% (May vary between batches)
Solubility
DMSO:55 mg/mL (171.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.22 mM)
Smiles
Oc1ccc (cc1O) -c1cc (OC2CCCC2) c2ccccc2n1
Molecular Formula
C20H19NO3
Molecular Weight
321.37
Storage Conditions
-20°C
Notes
For research use only.
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